Spinal Infection

1. Definition

  • Spinal infection involves infection of the vertebrae, intervertebral discs, epidural space, or paraspinal tissues.

2. Common Types

  • Spondylodiscitis
  • Vertebral osteomyelitis
  • Epidural abscess
  • Tuberculous spine (Pott’s disease)

3. Etiology

  • Bacterial infection (commonly Staphylococcus aureus)
  • Tuberculosis (especially in endemic regions)
  • Fungal infections in immunocompromised patients

Spinal Infection

4. Risk Factors

  • Diabetes mellitus
  • Immunosuppression and malignancy
  • Intravenous drug use
  • Recent spinal surgery or invasive procedures

5. Clinical Features

  • Persistent back or neck pain
  • Fever and constitutional symptoms
  • Local tenderness and restricted movements
  • Neurological deficits in advanced cases

6. Diagnosis

  • Raised inflammatory markers (ESR, CRP)
  • Blood cultures
  • MRI spine (gold standard)
  • CT-guided biopsy for organism identification

7. Management

  • Prolonged targeted antibiotic or antitubercular therapy
  • Bed rest and spinal immobilization
  • Nutritional support and control of comorbidities

8. Surgical Indications

  • Neurological deterioration
  • Spinal instability or deformity
  • Abscess causing neural compression
  • Failure of conservative treatment

9. Outcome

  • Early diagnosis and appropriate treatment lead to good outcomes
  • Delay may result in deformity, neurological deficit, or chronic pain